Launched in 2007, the institute is the first of its kind in Canada, combining the expertise of researchers in basic cancer biology and clinicians in veterinary medicine to take an integrated approach to cancer studies that cannot easily be matched in human research settings. The ICCI is dedicated to furthering the understanding of the cancer for the benefit of all species, including humans.
A key component of this groundbreaking initiative is the establishment of a world-class Animal Cancer Centre in the OVC Health Sciences Centre. The centre is dedicated to cancer diagnosis, treatment, teaching and clinical research.
ICCI Team (Left to Right): (left photo) Dr. Paul Woods (Co-Director), Dr. Kaya Skowronski (Previous Tumour Bank Coordinator); Dr. Vicky Sabine (Clinical Research Coordinator), Dr. Michelle Oblak (Co-Assistant Director), Dr. Geoff Wood (Co-Assistant Director) and Dr. Brenda Coomber (Co-Director); (right photo) Deirdre Stuart (Current Tumour Bank Coordinator).
Wright, T., Brisson, B. A., Wood, G. A., Oblak, M., Mutsaers, A. J., Sabine, V., Skowronski, K., Belanger, C., Tiessen, A., & Bienzle, D. (2019). Flow Cytometric Detection of Circulating Osteosarcoma Cells in Dogs. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 95(9), 997–1007. https://doi.org/10.1002/cyto.a.23847 Flow Cytometric Detection of Circulating Osteosarcoma Cells in Dogs. Funded partly by Pet Trust.
Craig, K., Wood, G. A., Keller, S. M., Mutsaers, A. J., & Wood, R. D. (2019). MicroRNA profiling in canine multicentric lymphoma. PloS one, 14(12), e0226357. https://doi.org/10.1371/journal.pone.0226357 MicroRNA profiling in canine multicentric lymphoma. Funded partly by Pet Trust.
Parissenti, A. M., Pritzker, L. B., Guo, B., Narendrula, R., Wang, S. X., Lin, L. L., Pei, J., Skowronski, K., Bienzle, D., Woods, J. P., Pritzker, K., & Coomber, B. L. (2019). RNA disruption indicates CHOP therapy efficacy in canine lymphoma. BMC veterinary research, 15(1), 453. https://doi.org/10.1186/s12917-019-2189-x RNA disruption indicates CHOP therapy efficacy in canine lymphoma. Funded partly by Pet Trust.
Deravi, N., Berke, O., Woods, J. P., & Bienzle, D. (2017). Specific immunotypes of canine T cell lymphoma are associated with different outcomes. Veterinary immunology and immunopathology, 191, 5–13. https://doi.org/10.1016/j.vetimm.2017.07.008
Weidner, N., Woods, J. P., Conlon, P., Meckling, K. A., Atkinson, J. L., Bayle, J., Makowski, A. J., Horst, R. L., & Verbrugghe, A. (2017). Influence of Various Factors on Circulating 25(OH) Vitamin D Concentrations in Dogs with Cancer and Healthy Dogs. Journal of veterinary internal medicine, 31(6), 1796–1803. https://doi.org/10.1111/jvim.14834
Calvalido, J., Wood, G. A., Mutsaers, A. J., Wood, D., Sears, W., & Woods, J. P. (2016). Comparison of serum cytokine levels between dogs with multicentric lymphoma and healthy dogs. Veterinary immunology and immunopathology, 182, 106–114. https://doi.org/10.1016/j.vetimm.2016.10.009
Mona Campbell Centre for Animal Cancer andICCI in the media:
ICCI Co-Assistant Director Geoff Wood recently had a “one health” study published inNature Communications comparing cancer genomes from human mucosal melanoma, canine oral melanoma and equine melanoma. This study was the first study to sequence equine tumours, and first to compare the genomes of the above three species (University of Guelph story here).
CTV W5 featured a story about Max, an OVC patient and participant in an ICCI-coordinated, NIH funded multi-centre trial for dogs with osteosarcoma. This story highlighted two human patients who benefited from research done in canines.
Nationalpost published an article on the important contribution that companion animal cancer patients provide by participating in clinical research studies to veterinary and human healthcare.
OVC Pet Trust– Help the pets we love, live longer, healthier lives! OVC Pet Trust is Canada’s first charitable fund dedicated to the health and well-being of companion animals.
Kennel to Cure– A research collective based at the OVC with collaborators and team members across Canada, focused on translational research between companion animal cancer research and human cancer research. Research focuses include pathobiology of tumourigenesis, novel therapeutics and personalized medicine, ethics and quality of life, and social, economic and logistical aspects of cancer search in Canada.
Smiling Blue Skies– A broad scope support and resource page for all things about canine cancer, its treatment, and research. Smiling Blue Skies offers 24/7 support to anyone whose life has been touched by cancer.
Ontario Veterinary College, University of Guelph, 50 Stone Road E., Guelph, ON, Canada, N1G 2W1
Email Contacts -- (Tumour Bank) firstname.lastname@example.org -- (Clinical Trials) email@example.com