** Please note this study is closed/completed and no longer recruiting patients **
Primary objective is to determine if one transfusion of leukoreduced (LR) packed red blood cells (PRBC) leads to less transfusion-associated inflammation compared to non-LR PRBC in dogs with critical illness, including Oncology patients, within the first 24 hours after transfusion. Secondary objective is to monitor survival and outcome differences between patients receiving LR and non-LR PRBC transfusions.
The Ontario Veterinary College maintains a Blood Bank, for patients in need of transfusion. Currently, blood at the OVC Blood Bank is not routinely “leukoreduced,” or filtered to remove white blood cells, prior to transfusion. However, this filtering technique may help reduce the risk of transfusion reactions in people and dogs.
- Study covers cost of complete blood count before & after transfusion (2hrs & 24hrs)
- Blood (before & after transfusion: 2 & 24hrs)
- Any dog with confirmed diagnosis of anemia receiving their first RBC transfusion @ OVC
- Previous transfusion
- Concurrent plasma transfusion
- Steroids/NSAIDs in past 2 weeks
- Dr. Shauna Blois (PI)
- Dr. Luis Bosch
Funded by OVC Pet Trust.
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