The OVC Veterinary Biobank (OVCVB) currently has over 32,500 aliquots from approximately 1850 oncology patients. The OVCVB follows strict confidentiality and ethical standards, and standard operating procedures to ensure samples are of highest quality. OVCVB controls every aspect of collection, storage and access to this unique repository of canine and feline tumour samples with de-identified clinical and diagnostic data. Samples are accessed through a simple application process.
Sample Types*
- Peripheral blood (Serum, plasma and buffy coat)
- Urine
- Tumour tissue: flash frozen, RNAlater, FFPE slides, or cryosections†
- Normal-adjacent tissue: flash frozen, RNAlater, or cryosections†
- Cell lines – see section below for more information
*complete sample sets are not available for all cases; please enquire
†discontinued but may have minimal availability; please enquire
The most prevalent tumour types banked
| Canine | Feline |
|---|---|
| Soft Tissue Sarcoma | Mammary Sarcoma |
| Osteosarcoma | Soft Tissue Sarcoma |
| Mast Cell Tumour | Lymphoma |
| Hemangiosarcoma | Osteosarcoma |
Clinical Data
To facilitate research on OVCVB samples, extensive clinical data is available for most cases. De-identified information includes:
- Patient signalment (breed, date of birth, sex)
- Pathological Diagnosis and Staging
- Treatment details (start and end dates, response, etc.)
- Outcome and progression of disease
- Pathology reports (histology, tumour size, grade)
*Our data is available in basic or full packages; please enquire for more details
Cell lines
Early passages from canine and feline primary tumour cell lines are available from approximately 40 different cases. Tumour types include:
- lung carcinoma
- hemangiosarcoma
- soft tissue sarcoma
- melanoma
- anal sac adenocarcinoma.
Please enquire about availability and pricing.
Quality Control Measures
OVCVB follows standard operating procedures based on best practices found on the International Society for Biological and Environmental Repositories (ISBER) to ensure samples are collected and stored properly to best preserve molecular integrity.
Quality Control is performed by a pathologist on all tumour tissue collected.
OVCVB follows strict collection and processing SOPs, such as:
- Tissues are frozen within 30 minutes of resection
- All cases are verified by a pathologist
- Sterility measures
- All samples are labelled with bar codes
- Any deviation from standard protocol is recorded in the sample file